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Clinical Development Infectious Diseases
Clinical Development Oncology
IL-7 has an excellent safety record demonstrated on more than 440 treated patients
IL-7 is a naturally occurring cytokine produced by lymphoid stromal cells
IL-7 receptor self regulates as T Cell becomes more activated, it deceases IL-7 receptor expression.
(Mazzucchelli and Durum – Nat. Review Immunol. 7:144 2007.)
The clinical tolerance is considered as good and easy to manage by our clinical investigators.
Most common side effects:
Injection site reactions
Occasional reversible grade I/II rash,
Rare transient elevated liver functions tests.
Active autoimmunity is a contraindication.
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