IL-7 is a naturally occurring cytokine produced by lymphoid stromal cells

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IL-7 receptor self regulates as T Cell becomes more activated, it deceases IL-7 receptor expression.
(Mazzucchelli and Durum – Nat. Review Immunol. 7:144 2007.)

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The clinical tolerance is considered as good and easy to manage by our clinical investigators.

 

                               

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Most common side effects:

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Injection site reactions

Occasional reversible grade I/II rash,

Rare transient elevated liver functions tests.

 

                               

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Active autoimmunity is a contraindication.